Background: Chronic Obstructive Pulmonary Disease (COPD) is associated with reduced exercise capacity, muscle weakness, and increased fatigue. Rehabilitation strategies including resistance training and muscle stretching may improve functional outcomes.

Objective: To evaluate the effect of resistance training combined with muscle stretching on functional capacity and fatigue in patients with COPD.

Methodology: An experimental interventional study was conducted on 30 COPD patients divided into two groups. Group A received resistance training with upper and lower limb stretching, while Group B received resistance training combined with respiratory muscle stretching. Outcome measures included Borg Scale (RPE), 6-Minute Walk Distance (6MWD), and FACIT Fatigue Scale.

Results: Both groups showed significant improvement in functional capacity and fatigue (p<0.0001). However, Group B demonstrated greater improvement in 6MWD and fatigue scores compared to Group A.