Introduction: Two-point discrimination is the combined cortical sensation. The assessment of TPD gives complete idea of the function of the nervous system as it involves tracts and cortical areas for the integrity. The assessment of the TPD is valuable for the diagnosis and prognosis of nervous regeneration and repair. The normal values of the TPD varies in the different geographical and anatomical areas of the body. It is necessary to establish normal values of the TPD for different age group population and various sites of the body for better clinical management.

Methodology: The literature search was done by key words such as Two-point discrimination, cortical sensation, normal values, healthy, adults on internet and various database and journals. From the literature the articles were selected using search strategy; irrelevant articles were excluded and only 7 articles of having Indian subjects were included in the study.

Result: From total 58 articles after removing duplicate articles and excluding irrelevant articles 7 articles were selected and reviewed. The data of year of publication, number of participants, age of subjects, body region of the measurement, result of normal values and additional point of discussion were extracted from the literature.