Background: Science defines energy as a spectrum made up of frequencies. Energy is identified as four basic types or forms in conventional science: electromagnetic, the gravitational, the strong and the weak nuclear force. ‘Prana’ is the name of energy that exists in our world and animates our physical bodies. This Prana Energy is the vital life force energy that gives us life and sustains our existence. The aim of the current study was to understand the effect of Pranic energy effect on Healthy and Non-Healthy people as Assessed by EPI / GDV / Bio- well.

Materials and Method: The current research is systemic review of literature on the topic done as per set inclusion and exclusion criteria, inclusive of PRISMA Guideline.All studies identified for inclusion were peer-reviewed and published in English. Articles were searched by using the keyword Prana, prana and health, prana and non-health, prana and disease, prana and EPI.

Result: After reviewing, all the studies show significant impact on human body. Most of the recipient of these osteopathic treatment experienced Increase in fingertip florescence area and average intensity, reduction in stress levels and improved blood pressure measurement. The perception of print and its effect on psychological well-being resulted revealed that 99.5 % of participants perceived pranic energy. Psychological wellbeing by awareness of air prana and the aura surrounding a tree among participants from different age group eexperiencing pranic energy led them into relaxed sensation, mentally strong.

Conclusions: After going all the available literature, it is evident that the free flow of Prana Energy is essential for a life of health, happiness and prosperity. In healing processes, it is observed that pranic energy negatively trapped in auric zone, chakras and bodies. In this way, one feels stressed, lethargic, depressed and dispassionate about one’s own existence. Pranic Healing can help move stuck energy. The problem of depleted energy can be reversed when one understands one’s own true nature as energy beings and the principles of Prana Energy flow. When the Prana Energy flow is corrected and balanced the body is able to heal itself in non-healthy people.