Purpose: To find out the effect of Covid -19 pandemic in non specific Low back pain among IT professionals who are working from home. Study design: Survey based Study Method: After screening on the basis of inclusion and exclusion criteria 276 participants were included in the study and the purpose and nature of the study explained to them. The study commenced following the approval of the ethical committee. A MODI questionnaire was generated using Google form which included specific and structured questions and the questionnaire related to their ergonomical difficulty before and duringcovid-19 pandemic while working on computer. Participants answered the questions and based on their response the results were postulated. Results: The effect of covid-19 pandemic in non-specific LBP among IT professionals who are working from home shows that the mean value is 58.69% and who are working from office the mean value shows that 50.36% there was statistical significant association with non-specific LBP. Conclusion: In the present study it was found that participants those worked from home had more non-specific low back pain than the participants who worked at worksite.