Background: The aim of the study is to explore the effectiveness of Feldenkrais exercise program in comparison with McKenzie exercise program on postural alignment and functional disability among students with upper crossed syndrome. Methods: In this comparative study, 30 female college students with upper crossed syndrome were selected and divided into two equal groups including Feldenkrais exercise group and Mc Kenzie exercise group. These two groups performed exercises of four weeks and five times per week. Postural alignment and functional disability using Craniovertebral angle and Neck disability index was assessed before and after intervention Result: Intergroup analysis was done using unpaired t-test which showed significant improvement in Group A subjects (Feldenkrais exercise program) for improving postural alignment (p<0.05) and decreasing functional disability (p<0.05) post treatment. Conclusion: Statistical analysis shows Feldenkrais exercise program were superior to McKenzie exercise program. Thus the study concluded that Feldenkrais exercise program should be beneficial in the rehabilitative phase of upper crossed syndrome.