Background: A significant contributor to chronic death and morbidity worldwide is chronic obstructive pulmonary disease (COPD), which many people experience for many years before passing away due to its sequelae. As a result of continued exposure to COPD risk factors and population ageing, the burden of COPD is expected to increase globally in the next decades. The goal of this study was to "detect if thoracic cage mobilizations are useful in treating COPD". Five individuals with chronic obstructive pulmonary disease took the part of trial for this reason. They were received thoracic mobilization treatment and conventional treatment. The training was continuing six sessions in intensive care unit "ICU". Each patient received mobilization treatments in addition to planned programmes of physical therapy. Arterial blood gases (ABG), chest expansion, dyspnoea Index, Computerized Tomography "CT" and COPD Assessment Test "CAT" questionnaire were measured before and after the intervention. Results: there was significance variance in chest expansion on the axillary and T10 level and there was a significance difference on pH 7.436±0.028. There was a decrease in the percentage of PaCO2 after the mobilization with mean value 67.12±3.12 mmHg and there was an increase of PaO2 after the treatment 65.95±15.56 mmHg. The results showed that there was a decrease in the CAT questionnaire after the treatment. This means that; the patient can go to their life without any problems. The mean value of CAT questionnaire pre-treatment was 28.4±4.27 and the mean value of CAT questionnaire post treatment was 16±6.63. Conclusion: Adding the thoracic cage mobilization to conventional treatment showed the difference in daily life of the patients after the treatment. This study was registered with registration NCT05448235. July, 2022; https://clinicaltrials.gov/ct2/show/NCT05448235 at Clinical Trial Registry.