Background and Purpose: Osteoarthritis is a major cause of impairment and disability among elderly. Physical therapy as a treatment in knee OA aims to increase ROM, decreased pain and improve daily functional activities. Knee O Apatient complains of pain, reduction in ROM and functional limitations. Study was done to assess effect of exercise along with exercise in patients with knee osteoarthritis. Material & Methodology: It was an experimental study. 30 patients were taken as per the inclusion and exclusion criteria, which were divided in two groups and given LLLT (3days/week) for 3 weeks followed by exercise protocol for 8 weeks as per allotted group. The pain, ROM, QOL was recorded post intervention. Results: There was statistical significant reduction in pain, increase ROM, increase QOL post intervention. (pvalue <o.oo6). On comparison of control vs experimental group there was a significant reduction in pain (WOMAC: 21.41±7.15vs 15.73±3.63), QOL (Lequesne questioannaire 7.57±2.32vs 5.37±1.73), ROM (128.73±4.95vs132.73±2.43) respectively. Discussion and Conclusion: Low Level Laser Therapy along with exercise is helpful in improvement of pain, functionality, activity and ROM in patients with OA knee.