Smart phone is a hand held portable device having a touch interface performing the function of a laptop and a handphone used for tasks such as internet browsing, gaming, texts, e- learning, social media and many more daily activities. Frequent usage may result in cumulative trauma disorders of the shoulder, elbow, wrist. Aim of this study was to find out the association of pain, strength with disability in upper limb among physiotherapy students using smartphone. This study will help to assess the influence of smartpohone usage leading to pain which eventually affects the hand grip strength leading to disability. Methodology-For this study 100 physiotherapy students in the age group of 18-25 experiencing pain in upper limb while using smartphone, using smartphone for minimum of 2 hours daily ans using smartphone from the past minimum 1 year. A questionnaire consisting of demographic details, NPRS, questions on usage of smartphone was administered. In students having pain hand pinch strength was carried out followed by administration of DASH questionnaire. Results indicated that out of the 100 participants 79% students were females and 21% were males, 97% students were right hand dominant and 3% students were left hand dominant, 73%students use their smartphone with both hands and 27% students use single handedly. Dast responses should that 20%students showed mild disability, 76% showed moderate disability, 4% showed no disability. Anova analysis showed that since p value<0.05 between the variables hence there is an association of pain, strength with disability in upper limb. Conclusion-It was concluded that smartphone usage in students showed reduced pinch strength with mild to moderate disability.