Purpose of the study was to find out the effect of yoga on selected lipid profile of mild intellectually persons. For this purpose fifteen (N=15) mild intellectual students were selected from special school in Coimbatore and their age was ranged between 14 to 18 years. Twelve week of yoga training was given to the subjects. The lipid profile namely total cholesterol, Triglyceride, High density lipoprotein, Low density lipoprotein and very low density lipoprotein were selected as independent variables. The data were collected before and after twelve weeks of intervention. t– Ratio was used to find out the significant difference between pre and post test. It was concluded from the result that the12 weeks of yoga program was made significant improvement in lipid profile on mild intellectually persons.