Background and Purpose: Smartphone's popularity has risen to such an extent in recent years that it is unimaginable for the people to stay away from it even for a while. The excessive usage has emerged to a condition termed as nomophobia or a form of behavioural addiction towards smartphone associated to the anxiety caused by detachment from the mobile network or inability to have access to a smartphone. Nomophobia is a modern age phobia introduced to our lives as a repercussion of the interaction between people and mobile phone. This study was conducted to find out the prevalence of nomophobia among the population in India aged above 18 years to 50 years. Material and Methodology: A 31-item nomophobia questionnaire was used to assess the prevalence of nomophobia among the medical students, also the purpose and in which context smartphone was used. The data was collected using a personal information form which includes the demographic variables, a self-administered google survey form for smartphone usage purpose and pattern, moreover form was distributed among the targeted audience via email, WhatsApp and other social media. A total of 200 valid responses were collected, entered into a Microsoft Excel spreadsheet, and analysed in SPSS software. Result: Almost 90% of the population has some or other symptoms of Nomophobia. About 90% of the population check their smartphone without reason. Majority (62.7%) of the participants were using smartphone for 3 to 6 hours in their leisure time (54.2%) and spent their maximum time on social media (52.7%). Eye strain (31.8%) was noted as the main health consequence of nomophobia. In addition to this, it was found that smart phone being user-friendly (87.1%), provided them with Easy access of information (92.5%), convenient way of working(83.1%).Also the Subjects experienced insecurity issues (53.2%) due to smartphone. Conclusion: The results of the study are suggestive of mobile phone dependence among medical students. The data is indicative of nomophobia to be an emerging problem of the modern era which needs attention. Thus, we can conclude that various activities done by youth confirms that they are addicted to smart phone.